| dcterms.contributor.author | De Rosa, Roberta | |
| dcterms.contributor.author | Polito, Maria Vincenza | |
| dcterms.contributor.author | Benvenga, Rossella Maria | |
| dcterms.contributor.author | De Angelis, Elena | |
| dcterms.contributor.author | Piscione, Federico | |
| dcterms.contributor.author | Galasso, Gennaro | |
| dc.date.accessioned | 2020-05-26T11:13:52Z | |
| dc.date.available | 2020-05-26T11:13:52Z | |
| dcterms.date.issued | 2017 | |
| dcterms.identifier.citation | De Rosa R, Polito MV, Benvenga R, De Angelis E, Piscione F, Galasso G. MicroRNs and cardiovascular diseases: from bench to bedside. Translational Medicine @ UniSa 2017, 17(3): 12-18. | it_IT |
| dcterms.identifier.issn | 2239-9747 | it_IT |
| dcterms.identifier.uri | http://www.translationalmedicine.unisa.it/index | it_IT |
| dcterms.identifier.uri | http://elea.unisa.it:8080/xmlui/handle/10556/4496 | |
| dcterms.identifier.uri | http://dx.doi.org/10.14273/unisa-2694 | |
| dc.description.abstract | MicroRNAs (microRNAs or miRs) are small, noncoding RNAs that control gene expression by binding to
and repressing specific mRNA target and have emered
as powerful regulators of many biological processes.
Understanding miRNAs-biology and functions may be
pivotal to get a better insight into pathophysiological
mechanisms responsible for a large number of morbid
conditions and may lay the foundations for the
development of novel therapeutic interventions.
Moreover, besides their intracellular functions, miRs are
present in the human circulation in a remarkably stable
cell-free form, and their plasmatic levels have been
proposed as biomarkers for several pathological
conditions. The present review aims to summarize the
current evidences with regard to biological role of
miRNAs in cardiovascular system and their
involvement in the pathogenesis of cardiovascular
diseases including atherosclerosis, heart failure and
pathological heart and vascular remodelling and to
highlight their potential use as novel biomarkers and as
therapeutic targets in cardiac and vascular diseases. | it_IT |
| dcterms.format.extent | P. 12-18 | it_IT |
| dc.language.iso | en | it_IT |
| dcterms.source | UniSa. Sistema Bibliotecario di Ateneo | it_IT |
| dcterms.subject | MicroRNAs | it_IT |
| dcterms.subject | Atherosclerosis | it_IT |
| dcterms.subject | Heart failure | it_IT |
| dcterms.subject | Vascular remodelling | it_IT |
| dcterms.subject | Biomarkers | it_IT |
| dcterms.subject | MicroRNAsbased therapeutics | it_IT |
| dcterms.title | MicroRNs and cardiovascular diseas es: from bench to beside | it_IT |
| dcterms.type | Article | it_IT |
