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Green processes based on SC-CO2: application to materials of biomedical interest
(Universita degli studi di Salerno, 2015-05-25)
This research is focused on the production of structures of biomedical interest using supercritical assisted processes: Supercritical freeze extraction, Supercritical gel drying and Supercritical phase separation. These ...
Nanostructured vectors for the transport of active molecules through biological membranes for pharmaceutical and nutraceutical applications
(Universita degli studi di Salerno, 2017-04-27)
Purpose of the PhD thesis was to develop dedicated lipid nanostructured vectors with tailored features (in terms of size, surface charge, load capability, stimuli responsive ability and stability) through the design of ...
Process optimization of a lignocellulosic multi-product biorefinery
(Universita degli studi di Salerno, 2016-05-31)
A methodology to reduce the complexity of the process optimization was applied to multiproduct biorefinery fed by lignocellulosic biomass. A process superstructure was built to consider alternative process pathways to ...
Continuous supercritical emulsion extraction: process characterization and optimization of operative conditions to produce biopolymer microspheres
(Universita degli studi di Salerno, 2012-07-04)
Controlled release systems for therapeutic drugs have received extensive attention in recent years, due to their great clinical potential. Biodegradable microspheres are well-recognized systems to control the release rate ...
Nanoencapsulation of bioactive compounds for food applications
(Universita degli studi di Salerno, 2012-06-19)
The increase in dietary-intake-related illnesses, such as obesity, cardiovascular diseases, hypertension, diabetes and cancer, have made in recent years the development of health-and-wellness promoting foods a priority of ...
The effect of temperature on flow properties of powders
(Universita degli studi di Salerno, 2012-06-18)
Changes of cohesive flow properties of powders at high temperature are observed in many industrial process units, such as fluidized bed reactors, granulators and dryers. Many authors investigated the behaviour of powders ...
Integration of pulsed electric fields technology in the biorefinery of agri-food wastes and microalgae
(Universita degli studi di Salerno, 2019-03-12)
Recently, the idea of valorizing industrial agro-food wastes and microalgal biomass, through an
efficient recovery of their major bioactive constituents to be used as ingredients in food, feed,
pharmaceutical and cosmetic ...
Production of pharmaceutical and nutraceutical formulations for bioavailability improvement using Supercritical Assisted Atomization
(Universita degli studi di Salerno, 2019-03-13)
Industrial interest is focused on the development of new pharmaceutical and nutraceutical formulations aimed at the enhancement of bioavailability of poorly water-soluble active compounds. Various factors influence the ...
Relevant phenomena and process parameters in granulation for manufacturing of pharmaceutical, nutraceutical and zootechnical products
(Universita degli studi di Salerno, 2019-03-13)
Wet granulation is a size enlargement process used in many fields, such as pharmaceutical, nutraceutical, zootecnichal, etc., due its ability to improve technological properties of the final product, compared to the powder ...
Optimization of a supercritical assisted process for the production of liposomes for industrial applications
(Universita degli studi di Salerno, 2019-03-11)
Liposomes are spherical vesicles made of a double lipidic layer that surrounds an inner aqueous core.
Several methods for the preparation of liposomes have been developed in the last decades. However, these
methods present ...