Show simple item record

dc.contributor.authorRossi, Francesca Wanda
dc.contributor.authorRivellese, Felice
dc.contributor.authorNapolitano, Filomena
dc.contributor.authorMosella, Francesca
dc.contributor.authorSelleri, Carmine
dc.contributor.authorMontuori, Nunzia
dc.contributor.authorDe Paulis, Amato
dc.date.accessioned2020-07-08T13:00:02Z
dc.date.available2020-07-08T13:00:02Z
dc.date.issued2020
dc.identifier.citationRossi FW, Rivellese F, Napolitano F, Mosella F, Selleri C, Montuori N, de Paulis A. Effects of polyurethane foam dressings as an add-on therapy in the management of digital ulcers in scleroderma patients. Translational Medicine @ UniSa 2020, 22(3): 10-14.it_IT
dc.identifier.issn2239-9747it_IT
dc.identifier.urihttp://www.translationalmedicine.unisa.it/indexit_IT
dc.identifier.urihttp://elea.unisa.it:8080/xmlui/handle/10556/4634
dc.identifier.urihttp://dx.doi.org/10.14273/unisa-2823
dc.description.abstractDigital ulcers (DUs) represent a severe and common complication occurring in patients affected by Systemic Sclerosis (SSc), with a consistent impact on the quality of life and often resulting in longer hospitalization than unaffected patients. Conventional treatment of SSc ulcers consists of both topical and systemic (oral or intravenous) pharmacological therapies. Several surgical options are also available, but there is overall a lack of official guidelines or recommendations. The aim of this study was to evaluate the efficacy of a novel local therapy based on polyurethane foam dressings, namely the Highly Hydrophilic Polyurethane Foam (HPF), in addition to the conventional pharmacological treatment, in a cohort of 41 SSc patients with at least one active ulcer. Our results showed that the addition of HPF to the conventional treatment based on systemic drugs induced i) a significant reduction in the number of active DUs (p=0.0034); ii) a significant reduction of the mean duration of ulcer-related hospitalization as compared with standard therapy (p=0.0001); iii) a significant improvement of patients’ Quality of Life, as evaluated through the Scleroderma Health Assessment Questionnaire (SHAQ) (p=0.00011). Therefore, in our experience, the combined management of DUs can improve both the onset of new DUs and DU’s healing thus leading to a better outcome.it_IT
dc.format.extentP. 10-14it_IT
dc.language.isoenit_IT
dc.sourceUniSa. Sistema Bibliotecario di Ateneoit_IT
dc.subjectSystemic sclerosisit_IT
dc.subjectDigital ulcersit_IT
dc.subjectPolyurethaneit_IT
dc.titleEffects of polyurethane foam dressings as an add-on therapy in the management of digital ulcers in scleroderma patientsit_IT
dc.typeArticleit_IT
 Find Full text

Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record