Cerca
Items 1-10 di 32
Synthesis and properties of linear and cyclic peptoids
(2012-03-26)
Le strutture e le attività metaboliche di tutte le cellule si basano su una vasta gamma di molecole comprendenti: amminoacidi, carboidrati, lipidi e nucleotidi, insieme alle forme polimeriche di questi composti. Ognuna di ...
Design e sintesi di analoghi delle azumammidi, potenti inibitori degli enzimi HDACs
(2011-03-07)
Le azumammidi sono cinque ciclopeptidi di origine marina, isolate nel 2003 da
Fusetani et al dalla spugna Mycale izuensis e brevettate dalla Yamanouchi Pharmaceutical.
L'interesse destato da questi metaboliti secondari è ...
Enzymatic synthesis of macrolactones
(2011-02-24)
Macrolactones are a large and structurally diverse class of compounds. Natural products having a
macrolactone structure have been isolated from many natural sources such as plants, insects,
marine organism and bacteria. ...
Synthesis, Structure and Properties of Cyclopeptoids and Cyclopeptides
(2014-01-29)
Aim of the research project has been the synthesis of cyclopeptides and cyclopeptoids in order to investigate their structural properties and catalytic activities.
In particular, studies of the arrangement and the cyclopeptoids ...
Total synthesis of terpenoidic unsatured dialdehydes and evaluation of their activity towards TRP receptors
(2012-02-02)
The aim of this PhD project has been to develop new synthetic strategies in
enantioselective preparation of natural products.
In particular my attention has been focused on preparation of some natural
metabolite, containing ...
Asymmetric synthesis of Heterocyclic Compounds through cascade Carbon-Carbon and Carbon-Heteroatom bond forming processes
(2023-06-06)
The aim of my PhD thesis was focused on the asymmetric synthesis of new heterocyclic compounds using
cascade and tandem processes involving the formation of new binding Carbon-Carbon and Carbon-
Heteroatom.
Heterocyclic ...
New applications of Ester/Amide surrogates in organic synthesis
(2021-04-22)
Masked esters/amides are scaffolds endowed with a great potential in the field of organic synthesis. This PhD
project has been conceived, in the context of non-covalent organocatalysis, with the aim to exploit unsaturated ...
Chiral Bioactive Cyclopeptoids: Concepts and Purposes
(2020-02-09)
Peptides are an endless source of inspiration for medicinal chemistry, as these biomacromolecules regulate a number of biological activities, acting as hormones, neurotransmitters, signalling molecules and so on. They show ...
New perspectives in phase transfer catalysis
(2020-02-11)
The increasing demand for the stereoselective synthesis of bioactive compounds in both industrial and academic research has led to the rapid development of a variety of diastereo- and enantio-selective processes using phase ...
Synthesis of Eco-Friendly Additives for Sustainable Tanning Processes
(2022-06-08)
Sustainability is a global level challenge for tanning industry whose
production is based on Cr(III) salts for more than 90%, negatively impacting
both biotic and abiotic factors in an ecosystem. Societal challenges ...