Over the last 30 years a growing interest has been direct toward the biomolecular recognition of calixarene derivatives and more in particular to the interaction with druggable target(s).1,2 The aim of this PhD thesis was ...

Water is a very important resource for human and ecosystem. However, in recent years the presence of pollutants, such as pharmaceuticals, cosmetics, personal cares, dyes, and pesticides deriving from industrial, agricultural, ...

Natural products rich in health-promoting compounds could represent new potential therapy strategy in many diseases. In the present study we focus our attention on Capsicum annuum L. cv Senise and Solanum aethiopicum L. ...

The steric and the electronic environment are the fundamental parameters that define the catalytic properties of any active site. For late transition metal catalysts, they determine polymer molecular weight and branching ...

The aim of my PhD thesis was focused on the asymmetric synthesis of new heterocyclic compounds using cascade and tandem processes involving the formation of new binding Carbon-Carbon and Carbon- Heteroatom. Heterocyclic ...

The main interactions characterizing the crystals of organic molecules are weak interactions such as hydrogen bonds, van der Waals forces, hydrophobic interactions, etc.1 Considering the weak nature of the forces involved, ...

Masked esters/amides are scaffolds endowed with a great potential in the field of organic synthesis. This PhD project has been conceived, in the context of non-covalent organocatalysis, with the aim to exploit unsaturated ...

Peptides are an endless source of inspiration for medicinal chemistry, as these biomacromolecules regulate a number of biological activities, acting as hormones, neurotransmitters, signalling molecules and so on. They show ...

The increasing demand for the stereoselective synthesis of bioactive compounds in both industrial and academic research has led to the rapid development of a variety of diastereo- and enantio-selective processes using phase ...

Dietary fat sources differently affect cellular metabolism, with different effects on metabolic disease risks. In the present PhD thesis, it was evaluated the effect of Omega-3 Polyunsaturated Fatty Acids (Omega-3 PUFAs), ...