Hyperpigmentation is the process by which an excess of melanin is produced by the skin. Typically, hyperpigmentation occurs as a result of stress, damage or prolonged inflammation of the skin. The most common cause is sun ...

Annexin 1 (ANXA1) is a multifunctional protein of 37 kDa, and represents the first characterized member of the annexin superfamily, so called since their main property is to bind (i.e. to annex) cell membranes in Ca2+-dependent ...

Glioma is a fatal disease characterized by uncontrolled cellular proliferation and it is the most common primary brain malignancy in adults. Despite years of research, malignant glioma remains one of the most aggressive ...

Con l’incremento del numero di persone affette da sindrome da immunodeficienza acquisita (AIDS), dell’uso di terapie immunosoppressive e del numero di pazienti affetti da varie forme di cancro e, dunque, fortemente debilitati ...

Il tratto gastrointestinale rappresenta una interfaccia tra il corpo e l’ambiente esterno. È dotato di sofisticati meccanismi che ne regolano la funzionalità e attua efficaci strategie per la sua protezione affidandosi a ...

My research project concerns the study of the molecular mechanisms involving microRNAs (miRNAs) in pathological processes such as tumors and cardiovascular diseases. miRNAs are small non-coding RNAs (sncRNAs) acting by ...

Diabetes is a metabolic alteration due to a decrease in activity of insulin. In particular, it may be a consequence of a reduced availability of this hormone, of an impediment to its normal action, or of a combination of ...

The urokinase type plasminogen activator (uPAR) is a three domain GPI-anchored cell surface receptor. uPAR expression is strongly up-regulated and represents a negative prognostic factor in various tumors, including ...

BAG3 protein, a member of BAG family of co-chaperones, has a pro-survival role in several tumor types. BAG3 anti-apoptotic properties rely on its characteristic to bind several intracellular partners, thereby modulating ...

The problem of data compression having specific security properties in order to guarantee user’s privacy is a living matter. On the other hand, high-throughput systems in genomics (e.g. the so-called Next Generation ...