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Design, synthesis and biological evaluation of new small-molecule modulators of proein lysine methyltransferases (PKMTs) 

Rescigno, Donatella (Universita degli studi di Salerno, 2018-04-20)
Histone lysine methyltransferases have crucial roles in a number of biological processes and human diseases by controlling gene expression and chromatin state. Within this family, the lysine methyltransferase G9a has emerged ...

Drug delivery to the lung in Cystic Fibrosis: deposition, dissolution, mucus interaction and microbiological evaluation of dry powder inhalers 

Manniello, Michele Dario (Universita degli studi di Salerno, 2018-04-05)
The inhalation therapy consists of a direct administration of drugs for the treatment of lung diseases. A formulation for inhalation is a valid option in the symptomatic management of pulmonary diseases typical of cystic ...

PGI products of Campania region: chemical and biological investigation of edible parts and by-products as potential sources of functional ingredients for herbal, nutraceutical and cosmetic formulations. 

Cerulli, Antonietta (Universita degli studi di Salerno, 2018-05-05)
This project is addressed to the definition of the chemical profile of selected PGI products of Campania region and related byproducts to highlight the presence of phytochemicals with health benefits. The species studied ...
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Molecular basis of cardiomiopathy 

Pecoraro, Michela (Universita degli studi di Salerno, 2018-04-05)
The normal heart rhythm is guaranteed by an important intercellular junctions system, named Gap Junction (GJs). Each GJs consists of two units called connexons formed by six specific trans-membrane proteins named connexins ...
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Computational design of new antimicrobial peptides 

Parisi, Rosaura (Universita degli studi di Salerno, 2018-04-13)
Antimicrobial peptides (AMP) are evolutionarily conserved components of the innate immune system. They have a broad spectrum of action against bacteria, fungi and viruses. Therefore, AMP are studied as probable substitutes ...
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Design and synthesis of bioactive small molecules by traditional and innovative methods 

Ciaglia, Tania (Universita degli studi di Salerno, 2018-03-28)
My PhD research plan concerns the exploration of the structural requirements determining TRPM8 modulation. We prepared a series of N-substituted tryptamines and identified two compounds acting, respectively, as an activator ...
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Chemical and biological study of natural substances active on the central nervous system 

Caputo, Lucia (Universita degli studi di Salerno, 2018-04-05)
The research project "Chemical and biological study of natural substances active on the Central Nervous System" has been focused on the possible effects of essential oils, their main constituents (in particular monoterpenes), ...
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Role of CD73 - A2A/A2B receptors axis in cancer 

Sorrentino, Claudia (Universita degli studi di Salerno, 2018-04-05)
The adenosinergic pathway plays a critical role in cancer development and progression, as well as in drug resistance to chemotherapy and/or targeted-therapy. The goal of this PhD thesis was to investigate and fully ...

Design, synthesis and biological activity of new target selective antitumoral agents 

Russo, Alessandra (Universita degli studi di Salerno, 2018-04-05)
Cancer development is a complex pathological process that exploits a variety of biological actors. The identification of new molecular entities able to interfere with new biological targets, involved in tumorigenesis, is ...
EleA themes by Ugsiba
 

 

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AuthorCaputo, Lucia (1)Cerulli, Antonietta (1)Ciaglia, Tania (1)Manniello, Michele Dario (1)Parisi, Rosaura (1)Pecoraro, Michela (1)Rescigno, Donatella (1)Russo, Alessandra (1)Sorrentino, Claudia (1)SubjectBIO/14 FARMACOLOGIA (2)BIO/15 BIOLOGIA FARMACEUTICA (2)CHIM/08 CHIMICA FARMACEUTICA (2)Activity (1)Adenosine (1)Adenyl cyclase (1)Antibiotic (1)Antimicrobial (1)Antitumoral (1)BAG3 (1)... View MoreDate Issued
2018 (9)
Has File(s)Yes (9)
EleA themes by Ugsiba