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Adrenergic mechanism in the control of endothelial function 

Sorriento, Daniela; Trimarco, Bruno; Iaccarino, Guido (2011)
There is considerable evidence that many disease are associated with endothelial dysfunction and reduced nitric oxide production such as hypertension, obesity, dyslipidemias, diabetes, heart failure, atherosclerosis. Notably ...
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A polymorphism within the promoter of the dopamine receptor D1 (DRD1 -48A7G) associates with impaired kidney function in white hypertensive patients 

Cipolletta, Ersilia; Ciccarelli, Michele; Izzo, Raffaele; Finelli, Rosa; Trimarco, Bruno; Iaccarino, Guido (2012)
Dopamine DRD1 receptor regulates renal function and vascular resistance. It plays a role in the pathogenesis of hypertension in animal models. In humans, the DRD1 gene presents a A-48G polymorphism associated to hypertension ...
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Redesigning Service Delivery for Hypertensive Patients: A Methodological Guideline to Improve the Management of Chronic Diseases 

Ippolito, Adelaide; Cannavacciuolo, Lorella; Ponsiglione, Cristina; De Luca, Nicola; Iaccarino, Guido; Illario, Maddalena (2014)
Best care is not necessarily the most expensive, but the most appropriate, and prevention is the most powerful tool to promote health. A novel approach might envision the reduction of hospital admittance (thus meeting a ...
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To NFkB or not to NFkB: the dilemma on how to inhibit a cancer cell fate regulator 

Sorriento, Daniela; Illario, Maddalena; Finelli, Rosa; Iaccarino, Guido (2012)
Nuclear factor B (NFB) is a transcription factor that plays an important role in carcinogenesis as well as in the regulation of inflammatory response. NFB is constitutively expressed in tumours where it induces the ...
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Dual role of grk5 in cancer development and progression 

Gambardella, Jessica; Franco, Antonietta; Del Giudice, Carmine; Fiordelisi, Antonella; Cipolletta, Ersilia; Ciccarelli, Michele; Trimarco, Bruno; Iaccarino, Guido; Sorriento, Daniela (2016)
GRK5 is a multifunctional protein that is able to move within the cell in response to various stimuli to regulate key intracellular signaling from receptor activation, on plasmamembrane, to gene transcription, in the ...
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Models for preclinical studies in aging-related disorders: one is not for all 

Santulli, Gaetano; Borras, Consuelo; Bousquet, Jean; Calzà, Laura; Cano, Antonio; Illario, Maddalena; Franceschi, Claudio; Liotta, Giuseppe; Maggio, Marcello; Molloy, William D.; Montuori, Nunzia; O’Caoimh, Rónán; Orfila, Francesco; Rauter, Amelia P.; Santoro, Aurelia; Iaccarino, Guido (2015)
Preclinical studies are essentially based on animal models of a particular disease. The primary purpose of preclinical efficacy studies is to support generalization of treatment–effect relationships to human subjects. ...
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Proceedings of the eip on aha: a3 action group on frailty 

Illario, Maddalena; Iaccarino, Guido; Piazza, Ornella; Menditto, Erica (2015)
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Rays sting: the acute cellular effects of ionizing radiation exposure 

Franco, Antonietta; Ciccarelli, Michele; Sorriento, Daniela; Napolitano, Luigi; Fiordelisi, Antonella; Trimarco, Bruno; Durante, Marco; Iaccarino, Guido (2016)
High-precision radiation therapy is a clinical approach that uses the targeted delivery of ionizing radiation, and the subsequent formation of reactive oxygen species (ROS) in high proliferative, radiation sensitive cancers. ...
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Implementing an ict-based polypharmacy management program in Italy 

Arcopinto, Michele; Cataldi, Mauro; De Luca, Vincenzo; Orlando, Valentina; Simeone, Giuseppe; D’Assante, Roberta; Postiglione, Alfredo; Guida, Antonella; Trama, Ugo; Illario, Maddalena; Coscioni, Enrico; Iaccarino, Guido; Cuccaro, Paula; D’Onofrio, Gaetano; Vigorito, Carlo; Cittadini, Antonio; Ferrara, Nicola; Menditto, Enrico (2017)
Although there is evidence of a growing awareness of the problem, no official policy statements or regulatory guidelines on polypharmacy have been released up to date by Italian Health Authorities. Medication review, ...
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Larger blood pressure reduction by fixed-dose compared to free dose combination therapy of ace inhibitor and calcium antagonist in hypertensive patients 

Visco, Valeria; Finelli, Rosa; Pascale, Antonietta Valeria; Giannotti, Rocco; Fabbricatore, Davide; Ragosa, Nicola; Ciccarelli, Michele; Iaccarino, Guido (2017)
The introduction of fixed combination of ACEi+CCB (Fixed) has significantly increased patients compliance and adherence to therapy. At the moment, however, there are no data suggesting the better control of once-daily fixed ...
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Iaccarino, Guido (16)
Illario, Maddalena (9)De Luca, Vincenzo (6)Cataldi, Mauro (4)Ciccarelli, Michele (4)Coscioni, Enrico (4)Sorriento, Daniela (4)Trimarco, Bruno (4)Abete, Pasquale (3)Bousquet, Jean (3)... View MoreSubjectCancer (2)Frailty (2)GRK5 (2)ICT (2)ACE Inhibitors (1)Active and healthy ageing (1)Ageing (1)Aging (1)Air pollution (1)Allergic rhinitis (1)... View MoreDate Issued2019 (5)2016 (3)2012 (2)2015 (2)2017 (2)2011 (1)2014 (1)Has File(s)Yes (16)
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