• Implementing an ict-based polypharmacy management program in Italy 

  Arcopinto, Michele; Cataldi, Mauro; De Luca, Vincenzo; Orlando, Valentina; Simeone, Giuseppe; D’Assante, Roberta; Postiglione, Alfredo; Guida, Antonella; Trama, Ugo; Illario, Maddalena; Coscioni, Enrico; Iaccarino, Guido; Cuccaro, Paula; D’Onofrio, Gaetano; Vigorito, Carlo; Cittadini, Antonio; Ferrara, Nicola; Menditto, Enrico (2017)

  Although there is evidence of a growing awareness of the problem, no official policy statements or regulatory guidelines on polypharmacy have been released up to date by Italian Health Authorities. Medication review, ...
• Egfr inhibition in a pretreated sacral chordoma: a rolefor erlotinib? Case report and a brief review of literature 

  Trapani, Dario; Conforti, Fabio; De Pas, Tommaso (2017)

  We describe the case of a 69-year old male with an EGFR- positive Imatinib refractory sacral chordoma with synchronous lung metastases, treated with erlotinib, a first- generation EGFR inhibitor. After disease progression ...
• Book review: R. Dingwall and S. Frost (eds.), health and safety in a changing world, Routledge. Evolving goals for health and safety in workplaces today 

  Cersosimo, Giuseppina (2017)
• Microvascular blood flow improvement in hyperglycemic obese adult patients by hypocaloric diet 

  Mastantuono, Teresa; Di Maro, Martina; Chiurazzi, Martina; Battiloro, Laura; Starita, Noemy; Nasti, Gilda; Lapi, Dominga; Iuppariello, Luigi; Cesarelli, Mario; D’Addio, Gianni; Colantuoni, Antonio (2016)

  The present study was aimed to assess the changes in skin microvascular blood flow (SBF) in newly diagnosed hyperglycemic obese subjects, administered with hypocaloric diet. Adult patients were recruited and divided ...
• 67 kDa laminin receptor (67LR) in normal and neoplastic hematopoietic cells: is its targeting a feasible approach? 

  Montuori, Nunzia; Pesapane, Ada; Giudice, Valentina; Serio, Bianca; Rossi, Francesca Wanda; De Paulis, Amato; Selleri, Carmine (2016)

  The 67 kDa laminin receptor (67LR) is a non-integrin cell surface receptor for laminin (LM) that derives from a 37 kDa precursor (37LRP). 67LR expression is increased in neoplastic cells and correlates with an enhanced ...
• Urokinase type plasminogen activator receptor (uPAR) as a new therapeutic target in cancer 

  Montuori, Nunzia; Pesapane, Ada; Rossi, Francesca Wanda; Giudice, Valentina; De Paulis, Amato; Selleri, Carmine; Ragno, Pia (2016)

  The urokinase (uPA)-type plasminogen activator receptor (uPAR) is a GPIanchored receptor that focuses urokinase (uPA) proteolytic activity on the cell surface. uPAR also regulates cell adhesion, migration and ...
• In vitro apoptotic effects of farnesyltransferase blockade in acute myeloid leukemia cells 

  Giudice, Valentina; Ricci, Pier Carlo; Marino, Luigi; Rocco, Mattia; Villani, G; Langella, Monica; Manente, Lisa; Seneca, Elisa; Ferrara, Idalucia; Pezzullo, Luca; Serio, Bianca; Selleri, Carmine (2016)

  Farnesyltransferase inhibitors (FTIs) are a class of oral anti-cancer drugs currently tested in phase I-II clinical trials for treatment of hematological malignancies. The in vitro effects of various FTIs (alpha-hydr ...
• The urokinase/urokinase receptor system in mast cells: effects of its functional interaction with fmlf receptors 

  Rossi, Francesca Wanda; Prevete, Nella; Rivellese, Felice; Napolitano, Filomena; Montuori, Nunzia; Postiglione, Loredana; Selleri, Carmine; De Paulis, Amato (2016)

  Mast cell and basophils express the high affinity receptor for IgE (FcRI) and are primary effector cells of allergic disorders. The urokinase (uPA)-mediated plasminogen activation system is involved in physiological ...
• Use of the directional atherectomy for the treatment of femoro-popliteal lesions in patients with critical lower limb ischemia 

  Bracale, Umberto Marcello; Vitale, Gaetano; Bajardi, Guido; Narese, Donatella; Dinoto, Ettore; Giribono, Anna Maria; Ferrara, Doriana; Del Guercio, Luca; Midiri, Massimo; Pecoraro, Felice (2016)

  Femoro-popliteal PTA for the treatment of critical limb ischemia is frequently associated with unsatisfactory procedural success rates while directional atherectomy (DCA) has improved success rate since claudicant ...
• Stress-first single photon emission computed myocardial perfusion imaging 

  Aquino, Carmen Imma; Scarano, Mariella; Squame, Fiorenzo; Casaburi, Giorgio; Nori, Stefania Lucia; Pace, Leonardo (2016)

  Background. Myocardial perfusion imaging (MPI) with single photon emission tomography (SPET) is widely used in coronary artery disease evaluation. Recently major dosimetric concerns have arisen. The aim of this study ...
• The european innovation partnership on active and healthy ageing synergies: protocol for a prospective observational study to measure the impact of a community-based program on prevention and mitigation of frailty (ICP –PMF) in community-dwelling older adults 

  Liotta, Giuseppe; Orfila, Francesc; Vollenbroek-Hutten, Miriam; Roller-Winsbergerm, Regina; Musian, D; Alvino, Sam; O'Caoimh, Ronan; Cano, Antonio; Molloy, William; Iaccarino, Guido; Marazzi, Maria Cristina; Inzerilli, Maria Chiara; Madaro, Olga; Paúl, Constança; Csonka, Peter; Menditto, Enrica; Maggio, Maria; Scarcella, Paola; Gilardi, Fabrizio; Lucaroni, Francesca; Abete, Pasquale; Girardi, Viviane; Barra, Rita; Palombi, Leonardo (2016)

  Aim of this paper is to describe the protocol of the study “Impact of a Community-based Program on Prevention and Mitigation of Frailty in communitydwelling older adults” developed in the framework of the European ...
• Effect of α2-adrenergic agonists and antagonists on cytokine release from human lung macrophages cultured in vitro 

  Piazza, Ornella; Staiano, Rosaria I.; De Robertis, Edoardo; Conti, Guido; Di Crescenzo, Vincenzo; Loffredo, Stefania; Marone, Giancarlo; Zito Marinosci, Geremia; Cataldi, Mauro (2016)

  The most trusted hypothesis to explain how α2-adrenergic agonists may preserve pulmonary functions in critically ill patients is that they directly act on macrophages by interfering with an autocrine/paracrine adrenergic ...
• Evaluation of symptoms and prevention of cancer in menopause: the value of vulvar exam 

  Palumbo, Anna Rita; Fasolino, Carmine; Santoro, Giuseppe; Gargano, Virginia; Rinaldi, Maurizio; Arduino, Bruno; Belli, Mario; Guida, Maurizio (2016)

  Vulvar and vaginal atrophy (VVA), is a chronic medical condition experienced by postmenopausal women, with prevalence estimated ranging from 10% to 50% [1]. VVA is characterized by a constellation of symptoms, that may ...
• Prolonged complete hematologic response in relapsed/refractory T-large granular lymphocyte leukemia after bendamustine treatment 

  Rosamilio, Rosa; Giudice, Valentina; Ferrara, Idalucia; Annunziata, Silvana; Pezzullo, Luciano; Villani, G; Baldi, Carlo Eugenio; Guariglia, Roberto; Rocco, Mattia; Selleri, Carmine (2016)

  T-large granular lymphocyte leukemia (T-LGLL) is a chronic clonal proliferation of effector memory cytotoxic CD3+CD57+CD56- T cells and the current guidelines suggest immunosuppressive therapy as first-line therapy, ...
• Quality of life perception in type 2 diabetes 

  Petri, Cristian; Stefani, Laura; Bini, Vittorio; Maffulli, Nicola; Frau, Stefania; Mascherini, Gabriele; De Angelis, Massimiliano; Galanti, Giorgio (2016)

  Purpose: Lifestyle analysis is often used for primary and secondary prevention in many chronic metabolic diseases, including diabetes. Questionnaires are simple and common methods for first investigation risk of factors ...
• Prefazione 

  Piacentini, Marcello (2019)
• Il Sessantotto a cavallo tra i blocchi: socialismi dal volto umano a Est e a Ovest 

  Lomellini, Valentine (2019)

  The article investigates the political change of the 1970s, due to the emergence of new political movements, and their dialogue with political parties. In particular, it provides an in-depth analysis of the relationship ...
• Pensare la Primavera di Praga: tra disillusione, lutto e melanconia. 

  Kolář, Pavel (2019)

  This essay seeks to raise the question of how the Prague Spring and its suppression mattered for the subsequent history of the European Left. Did its defeat, by allegedly expelling any genuinely democratic socialism into ...
• L’eco della Primavera di Praga nella produzione letteraria samizdat: il caso dei Fejetony 

  Mella, Stefania (2019)

  To commemorate the Prague Spring, the Czech writer and journalist Ludvík Vaculík (1926- 2015) decided in 1968 to devote a short prose text (fejeton) to the real spring season and to the metaphorical one, which would be ...
• Tra Disgelo e Primavera in Cecoslovacchia: breve sonda nel mondo delle riviste letterarie 

  D’Amico, Tiziana (2019)

  The present work aims to investigate the period before the Prague Spring (1968) and the tension between culture and politics through the study of one particular cultural agent, the literary magazines. In particular, the ...

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