• Leg fracture associated with synostosis of interosseous membrane during running in a soccer player 

  Oliva, Francesco; Buharaja, Rodrigo; Iundusi, Riccardo; Tarantino, Umberto (2017)

  ntroduction - Leg fractures may occur frequently in sport injuries but it is very rare to find this kind of injury associated with interosseous membrane synostosis. This case report describes a unique case of 42 B1.2 ...
• Elective orthopaedic and trauma patients in southern italy are vitamin d deficient. A pilot study. 

  Foccillo, Antonio; Aicale, Rocco; Maffulli, Nicola (2017)

  Many patients present with Vitamin D (Vit d; 25 (OH) D) deficiency on admission to hospital. The present study evaluated the levels of serum concentration of 25 (OH) D in patients undergoing elective arthroplasty of the ...
• MicroRNs and cardiovascular diseas es: from bench to beside 

  De Rosa, Roberta; Polito, Maria Vincenza; Benvenga, Rossella Maria; De Angelis, Elena; Piscione, Federico; Galasso, Gennaro (2017)

  MicroRNAs (microRNAs or miRs) are small, noncoding RNAs that control gene expression by binding to and repressing specific mRNA target and have emered as powerful regulators of many biological processes. Understanding ...
• Transcatheter implantable devices to monitoring of elevated left atrial pressures in patients with chronic heart failure 

  De Rosa, Roberta; Piscione, Federico; Schranz, Dietmar; Citro, Roberta; Iesu, Severino; Galasso, Gennaro (2017)

  Elevated left atrial (LA) pressures are associated with poor prognosis in heart failure (HF). Invasive monitoring of LA-pressures and direct mechanical LAdecompression are associated with functional improvement in ...
• SiRNA delivery for control of cyclin d1 and e2f1 expression in crohn’s disease 

  Russo, Ilaria; Carrizzo, Albino; Bochicchio, Sabrina; Piazza, Ornella; Lamberti, Gaetano; Barba, Anna Angela; Vecchione, Carmine; Zeppa, Pio; Iovino, Paola; Bucci, Cristina; Santonicola, Antonella; Ciacci, Carolina (2017)

  Evidence in inflammatory bowel diseases (IBD) supports a connection between inflammation and cancer due to the alteration of the cell cycle with loss of control at the G1/S checkpoint. In this study, we analyze ...
• Mean reticolocyte hemoglobin content index plays a key role to identify children who are carriers of β –thalassemia 

  Vicinanza, Paolo; Vicinanza, Mariella; Cosimato, Vincenzo; Terracciano, Daniela; Cancellario, Sergio; Massari, Angelo; Danise, Paolo; Selleri, Carmine; Serio, Bianca (2017)

  Reticulocyte (r) and red blood cell (RBC) indices provide reliable parameters for screening and monitoring iron deficiency anemia (IDA) patients and β-thalassemia trait (BTT) carriers. The aim of this study is to ...
• Pilot study on epigenetic response to a mind-body treatment 

  Cozzolino, Mauro; Guarino, Francesco; Castiglione, Stefano; Cicatelli, Angela; Celia, Giovanna (2017)

  In the last years, epigenetics and functional genomics methods to evaluate the genomic effects and mechanisms of mind-body therapies have increasingly grown. DNA microarray technology has been used to show the involvement ...
• Dexmedetomidine: current role in burn ICU 

  Scibelli, Gennaro; Maio, Lucia; Sasso, Maiara; Lanza, Alessandro; Savoia, Giorgio (2017)

  Dexmedetomidine (DEX) is a relatively recent a2-adrenergic agonist which provides sedation, anxiolysis and analgesia with much less respiratory depression than other sedatives. These characteristics have implemented the ...
• Obesity and obesity related diseases, sugar consumption and bad oral health: a fatal epidemic mixture. The pediatric and odontologist point of view 

  Delli Bovi, Anna Pia; Di Michele, Laura; Laino, Giuliana; Vajro, Pietro (2017)

  Obesity and dental caries are increasingly widespread pathologies. The former is growing so rapidly that the WHO classified its trend as an “epidemic”. Both are triggered by a number of well known common etiologic factors ...
• Larger blood pressure reduction by fixed-dose compared to free dose combination therapy of ace inhibitor and calcium antagonist in hypertensive patients 

  Visco, Valeria; Finelli, Rosa; Pascale, Antonietta Valeria; Giannotti, Rocco; Fabbricatore, Davide; Ragosa, Nicola; Ciccarelli, Michele; Iaccarino, Guido (2017)

  The introduction of fixed combination of ACEi+CCB (Fixed) has significantly increased patients compliance and adherence to therapy. At the moment, however, there are no data suggesting the better control of once-daily ...
• Implementing an ict-based polypharmacy management program in Italy 

  Arcopinto, Michele; Cataldi, Mauro; De Luca, Vincenzo; Orlando, Valentina; Simeone, Giuseppe; D’Assante, Roberta; Postiglione, Alfredo; Guida, Antonella; Trama, Ugo; Illario, Maddalena; Coscioni, Enrico; Iaccarino, Guido; Cuccaro, Paula; D’Onofrio, Gaetano; Vigorito, Carlo; Cittadini, Antonio; Ferrara, Nicola; Menditto, Enrico (2017)

  Although there is evidence of a growing awareness of the problem, no official policy statements or regulatory guidelines on polypharmacy have been released up to date by Italian Health Authorities. Medication review, ...
• Egfr inhibition in a pretreated sacral chordoma: a rolefor erlotinib? Case report and a brief review of literature 

  Trapani, Dario; Conforti, Fabio; De Pas, Tommaso (2017)

  We describe the case of a 69-year old male with an EGFR- positive Imatinib refractory sacral chordoma with synchronous lung metastases, treated with erlotinib, a first- generation EGFR inhibitor. After disease progression ...
• Book review: R. Dingwall and S. Frost (eds.), health and safety in a changing world, Routledge. Evolving goals for health and safety in workplaces today 

  Cersosimo, Giuseppina (2017)
• Microvascular blood flow improvement in hyperglycemic obese adult patients by hypocaloric diet 

  Mastantuono, Teresa; Di Maro, Martina; Chiurazzi, Martina; Battiloro, Laura; Starita, Noemy; Nasti, Gilda; Lapi, Dominga; Iuppariello, Luigi; Cesarelli, Mario; D’Addio, Gianni; Colantuoni, Antonio (2016)

  The present study was aimed to assess the changes in skin microvascular blood flow (SBF) in newly diagnosed hyperglycemic obese subjects, administered with hypocaloric diet. Adult patients were recruited and divided ...
• 67 kDa laminin receptor (67LR) in normal and neoplastic hematopoietic cells: is its targeting a feasible approach? 

  Montuori, Nunzia; Pesapane, Ada; Giudice, Valentina; Serio, Bianca; Rossi, Francesca Wanda; De Paulis, Amato; Selleri, Carmine (2016)

  The 67 kDa laminin receptor (67LR) is a non-integrin cell surface receptor for laminin (LM) that derives from a 37 kDa precursor (37LRP). 67LR expression is increased in neoplastic cells and correlates with an enhanced ...
• Urokinase type plasminogen activator receptor (uPAR) as a new therapeutic target in cancer 

  Montuori, Nunzia; Pesapane, Ada; Rossi, Francesca Wanda; Giudice, Valentina; De Paulis, Amato; Selleri, Carmine; Ragno, Pia (2016)

  The urokinase (uPA)-type plasminogen activator receptor (uPAR) is a GPIanchored receptor that focuses urokinase (uPA) proteolytic activity on the cell surface. uPAR also regulates cell adhesion, migration and ...
• In vitro apoptotic effects of farnesyltransferase blockade in acute myeloid leukemia cells 

  Giudice, Valentina; Ricci, Pier Carlo; Marino, Luigi; Rocco, Mattia; Villani, G; Langella, Monica; Manente, Lisa; Seneca, Elisa; Ferrara, Idalucia; Pezzullo, Luca; Serio, Bianca; Selleri, Carmine (2016)

  Farnesyltransferase inhibitors (FTIs) are a class of oral anti-cancer drugs currently tested in phase I-II clinical trials for treatment of hematological malignancies. The in vitro effects of various FTIs (alpha-hydr ...
• The urokinase/urokinase receptor system in mast cells: effects of its functional interaction with fmlf receptors 

  Rossi, Francesca Wanda; Prevete, Nella; Rivellese, Felice; Napolitano, Filomena; Montuori, Nunzia; Postiglione, Loredana; Selleri, Carmine; De Paulis, Amato (2016)

  Mast cell and basophils express the high affinity receptor for IgE (FcRI) and are primary effector cells of allergic disorders. The urokinase (uPA)-mediated plasminogen activation system is involved in physiological ...
• Use of the directional atherectomy for the treatment of femoro-popliteal lesions in patients with critical lower limb ischemia 

  Bracale, Umberto Marcello; Vitale, Gaetano; Bajardi, Guido; Narese, Donatella; Dinoto, Ettore; Giribono, Anna Maria; Ferrara, Doriana; Del Guercio, Luca; Midiri, Massimo; Pecoraro, Felice (2016)

  Femoro-popliteal PTA for the treatment of critical limb ischemia is frequently associated with unsatisfactory procedural success rates while directional atherectomy (DCA) has improved success rate since claudicant ...
• Stress-first single photon emission computed myocardial perfusion imaging 

  Aquino, Carmen Imma; Scarano, Mariella; Squame, Fiorenzo; Casaburi, Giorgio; Nori, Stefania Lucia; Pace, Leonardo (2016)

  Background. Myocardial perfusion imaging (MPI) with single photon emission tomography (SPET) is widely used in coronary artery disease evaluation. Recently major dosimetric concerns have arisen. The aim of this study ...

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