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Adrenergic mechanism in the control of endothelial function
(2011)
There is considerable evidence that many disease are associated with endothelial dysfunction and reduced nitric oxide production such as hypertension, obesity, dyslipidemias, diabetes, heart failure, atherosclerosis. Notably ...
To NFkB or not to NFkB: the dilemma on how to inhibit a cancer cell fate regulator
(2012)
Nuclear factor B (NFB) is a transcription
factor that plays an important role in carcinogenesis as well
as in the regulation of inflammatory response. NFB is
constitutively expressed in tumours where it induces ...
Rays sting: the acute cellular effects of ionizing radiation exposure
(2016)
High-precision radiation therapy is a clinical approach that uses the targeted delivery of ionizing radiation, and the subsequent formation of reactive oxygen species (ROS) in high proliferative, radiation sensitive cancers. ...
Dual role of grk5 in cancer development and progression
(2016)
GRK5 is a multifunctional protein that is able to move within the cell in response to various stimuli to regulate key intracellular signaling from receptor activation, on plasmamembrane, to gene transcription, in the ...