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Design, synthesis and biological evaluation of new small molecule modulators of Arginine methyltransferases 

Milite, Ciro (2011-02-21)
The methylation of arginine residues is a prevalent post-translational modification, found on both nuclear and cytoplasmic proteins, catalyzed by the protein arginine N-methyltransferase (PRMT) family of enzymes. To date ...
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Design and synthesis of “small molecules” as antiviral and radiotracer agents 

Sellitto, Grazia (2011-03-28)
The present Ph.D. project was divided into different work parts, in a way that helps to understand and define the goals of this project. In particular: I) Design, synthesis and evaluation of antiviral activity of Arbidol ...
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The design and synthesis of novel N-heterocyclic compounds, and their evaluation of anti-cancer and anti-viral activity 

More, Vijaykumar (2014-05-21)
The thesis entitled “The design and synthesis of novel N-heterocyclic compounds, and their evaluation of anti-cancer and anti-viral activity" is divided into three chapters. The title of the thesis clearly reflects the ...
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Biophysical investigation of biomolecules in bio-membrane models 

Di Marino, Sara (2012-05-30)
Many drugs are available for the treatment of systemic or superficial mycoses, but only a limited number of them are effective antifungal drugs, devoid of toxic and undesirable side effects. Therefore there remains an ...
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Design, synthesis and biological evaluation of new non-nucleosidic inhibitors od DNA methyltransferases 

Viviano, Monica (2013-04-03)
The inactivation of tumor suppressor genes, which often results from epigenetic silencing associated with DNA hypermethylation, plays a pivotal role in the development of most forms of human cancer. Moreover, there are ...
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Characterization and biological properties of Citrus industrial derivatives and waste products for the formulation of nutraceuticals 

Pagano, Francesco (2015-03-16)
Polyphenols are natural chemical compounds, common in higher plants as and particularly known and appreciated for their health properties. We focused attention on Citrus bergamia, Citrus sinensis, Mela annurca and Vitis ...
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Analysis and evaluation of potential nutracentical milk and dairy products derived from the Centrale del latte di Salerno 

Pepe, Giacomo (2015-03-16)
The main objective of my PhD has been focused to the analysis and characterization of milk and dairy products derived from “Centrale del Latte di Salerno” in order to assess their potential use as dietary supplements and ...
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Isolation, characterization and biologica! evaiuation of bioactive compounds from compiex matrices with high nutraceutica! vaiue 

Basilicata, Manuela Giovanna (2021-06-17)
My PhD project based its main objective on the isolation, the characterization and the biological evaluation of bioactive compounds deriving from food matrices of animal and vegetable origin typical of the Mediterranean ...
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Onconutraceutics and personalized medicine: isolation, characterization, pharmacokinetics and biological evaluation of antiproliferative compounds from complex natural matrices 

Salviati, Emanuela (2021-06-06)
The PhD research project aims to the study of novel onconutraceuticals obtained from natural matrices for their potential use in the prevention and as valid support to the pharmacological therapies for the treatment of ...
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Design, synthesis, biological evaluation and binding studies of new small-molecule modulators of KDMs (lysine-specific demethylases) 

Balzano, Amodio Luca (2017-03-27)
JHDMs (JmjC-domain-containing histone demethylases) are the largest class of demethylase enzymes, contain a Jumonji C (JmjC) domain and catalyze lysine demethylation of histones through an oxidative reaction that requires ...
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AuthorBalzano, Amodio Luca (1)Basilicata, Manuela Giovanna (1)Botta, Antonio (1)Bruno, Ferdinando (1)Cannavacciuolo, Ciro (1)Caporale, Angelamaria (1)Ciaglia, Tania (1)Cianciulli, Agostino (1)Cipriano, Alessandra (1)Di Cristo, Francesca (1)... View MoreSubject
CHIM/08 CHIMICA FARMACEUTICA (36)
Epigenetics (4)Epigenetic (2)FIV (2)Inhibitors (2)NMR (2)Synthesis (2)5-lipoxygenase (1)Activity (1)Alimenti funzionali (1)... View MoreDate Issued2020 - 2023 (11)2011 - 2019 (25)Has File(s)
Yes (36)
EleA themes by Ugsiba