Cerca
Items 21-29 di 29
Characterization and biological properties of Citrus industrial derivatives and waste products for the formulation of nutraceuticals
(Universita degli studi di Salerno, 2015-03-16)
Polyphenols are natural chemical compounds, common in higher plants as and particularly known and appreciated for their health properties. We focused attention on Citrus bergamia, Citrus sinensis, Mela annurca and Vitis ...
NMR study of protein-ligand interaction
(Universita degli studi di Salerno, 2015-03-11)
My PhD project was focused on the study of protein-ligands interactions using different NMR techniques. NMR has a long history in drug discovery and hit-to-lead optimization. Compared to many other biophysical techniques, ...
Design, synthesis and biological evaluation of new small molecules with anti-inflammatory activity
(Universita degli studi di Salerno, 2015-03-18)
Per lipossigenasi (nota più comunemente con l'abbreviazione di LOX o LO) si intende una famiglia eterogenea di enzimi in grado di perossidare i lipidi e di causare l'ossigenazione di acidi grassi polinsaturi trasformandoli, ...
Design and synthesis of bioactive small molecules by traditional and innovative methods
(Universita degli studi di Salerno, 2018-03-28)
My PhD research plan concerns the exploration of the structural requirements determining TRPM8 modulation. We prepared a series of N-substituted tryptamines and identified two compounds acting, respectively, as an activator ...
Structural investigation of gp36-MPER in membrane mimicking systems
(Universita degli studi di Salerno, 2019-05-07)
FIV is a lentivirus that resembles the Human Immunodeficiency Virus (HIV). The lentiviral envelope glycoproteins (gp41 in HIV and gp36 in FIV) mediate virus entry by interacting with specific receptors present at the cell ...
Onconutraceutics and personalized medicine: isolation, characterization, pharmacokinetics and biological evaluation of antiproliferative compounds from complex natural matrices
(Universita degli studi di Salerno, 2021-06-06)
The PhD research project aims to the study of novel onconutraceuticals obtained from natural matrices for their potential use in the prevention and as valid support to the pharmacological therapies for the treatment of ...
Isolation, characterization and biologica! evaiuation of bioactive compounds from compiex matrices with high nutraceutica! vaiue
(Universita degli studi di Salerno, 2021-06-17)
My PhD project based its main objective on the isolation, the characterization and the biological evaluation of bioactive compounds deriving from food matrices of animal and vegetable origin typical of the Mediterranean ...
Rational design, synthesis and in vitro evaluation of cell-active chemical probes for bromodomain-containing proteins Alessandra
(Universita degli studi di Salerno, 2021-06-25)
Bromodomains (BRDs) are epigenetic readers able to selectively recognize the acetylated lysine residues on histone and non-histone proteins. Through their activity, bromodomain-containing proteins (BRDs) are involved in a ...
Development of analytical strategies for phytochemical investigation of «superfoods», with particular attention to Botanicals.
(Universita degli studi di Salerno, 2022-04-27)
There is a great attention to functional foods exerting health benefits. In this frame the claim ‘superfood’ to
characterize products with high nutritional value and bioactive phytochemicals is more and more used. In ...