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Development and validation of analytical methods for therapeutic drug monitoring
(Universita degli studi di Salerno, 2019-07-25)
The U.S. Food and Drug Administration defines as Precision or Personalized Medicine (PM) an
innovative therapeutic approach that tailors therapy and prevention on patients based on inter-individual
variabilities in ...
“Transcutaneous laryngeal ultrasonography: a reliable, non-invasive and inexpensive preoperative method in the evaluation of vocal cords motility. A prospective multicentric analysis on a large series and an analysis of Literature”
(Universita degli studi di Salerno, 2019-07-24)
INTRODUCTION Benign and malignant thyroid diseases affect a large population worldwide.
Total Thyroidectomy is one of the most commonly performed intervention in general surgery. The
most feared and dangerous complication ...
Ruolo del Ruxolitinib nel cross-talk tra cellule staminali mesenchimali e microambiente midollare nella mielofibrosi
(Universita degli studi di Salerno, 2019-03-13)
Introduction;
Mesenchymal stem cells (Mesenchymal Stem Cells, MSC) are one of the most studied and well-characterized adult stem cell populations. They are excellent candidates in regenerative medicine, mainly because ...
“Functional MRI Study of Human Gustatory Cortex: Technological Advancements and Applications to Basic and Clinical Neurosciences”
(Universita degli studi di Salerno, 2019-03-08)
The purpose of brain plasticity is generating adaptive behaviours while
predicting, interpreting, and responding to more and more complex
tasks. Some of the most riveting questions in neuroscience revolve
around the ...
Target-based study to identify new bioactive diterpenes
(Universita degli studi di Salerno, 2019-04-16)
Target identification and mechanism of action studies of plant-derived compounds play a critical role in drug discovery. The knowledge of the bioactivity of natural compounds can lead to a number of advantages: first of ...
The Winnie-APCmin as an innovative tool to investigate the axis between inflammation and colorectal cancer
(Universita degli studi di Salerno, 2019-05-07)
During these last three yeas of PhD we aimed to create a new murine model of spontaneous inflammatory-induced colorectal cancer a combining the genetic susceptibility of the APCMin model and the chronic intestinal inflammation ...
Computational chemistry techniques for the design and the synthesis of molecules with anti-inflammatory and anti-tumor activity
(Universita degli studi di Salerno, 2019-06-18)
In the last few years, computational chemistry has played an important role in disclosing novel compounds with relevant biological activity. Inflammation and cancer processes have been recently linked, and the identification ...
Technologies for the development of health products based on up-cycling of agro-food by-products
(Universita degli studi di Salerno, 2019-04-12)
The agro-industrial processing produces large volumes of wastes and by-products. In recent years, wastes and by-products have attracted attention as an excellent renewable source of active compounds with beneficial effects ...
Functional Characterization of Candida albicans Hst3p histone deacetylase
(Universita degli studi di Salerno, 2019-05-07)
The unicellular eukaryotic organism Candida albicans is one of the most important fungi in medicine, used as experimental model to study fungal pathologies and the underlying biology of dimorphic fungi. This fungus is a ...
Development of technological approaches based on supercritical fluids for the production of polymeric micro-nano particulate systems for wound healing
(Universita degli studi di Salerno, 2019-04-12)
The PhD project titled “Development of technological approaches based on supercritical fluids for the production of polymeric micro-nano particulate systems for wound healing” aimed to develop novel formulations for topical ...