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Metabolic control of FoxP3 expression in human regulatory T cells
(Universita degli studi di Salerno, 2017-05-30)
Regulatory CD4+CD25+ T (Treg) cells play a central role in the maintenance of immune self-tolerance and homeostasis. Although Treg cells operate through multiple mechanisms, it appears that the expression of the transcription ...
Unraveling biomarkers in Parkinson’s disease: the role of Insulin-like growth factor-1 (IGF-1) and DAT imaging
(Universita degli studi di Salerno, 2018-02-28)
Parkinson's disease (PD) is the second most common neurodegenerative disease after Alzheimer's
disease, affecting up to 10 million individuals worldwide. Although symptomatic treatment
ameliorates motor symptoms, currently ...
Development and validation of analytical methods for therapeutic drug monitoring
(Universita degli studi di Salerno, 2019-07-25)
The U.S. Food and Drug Administration defines as Precision or Personalized Medicine (PM) an
innovative therapeutic approach that tailors therapy and prevention on patients based on inter-individual
variabilities in ...
“Transcutaneous laryngeal ultrasonography: a reliable, non-invasive and inexpensive preoperative method in the evaluation of vocal cords motility. A prospective multicentric analysis on a large series and an analysis of Literature”
(Universita degli studi di Salerno, 2019-07-24)
INTRODUCTION Benign and malignant thyroid diseases affect a large population worldwide.
Total Thyroidectomy is one of the most commonly performed intervention in general surgery. The
most feared and dangerous complication ...
Ruolo del Ruxolitinib nel cross-talk tra cellule staminali mesenchimali e microambiente midollare nella mielofibrosi
(Universita degli studi di Salerno, 2019-03-13)
Introduction;
Mesenchymal stem cells (Mesenchymal Stem Cells, MSC) are one of the most studied and well-characterized adult stem cell populations. They are excellent candidates in regenerative medicine, mainly because ...
“Functional MRI Study of Human Gustatory Cortex: Technological Advancements and Applications to Basic and Clinical Neurosciences”
(Universita degli studi di Salerno, 2019-03-08)
The purpose of brain plasticity is generating adaptive behaviours while
predicting, interpreting, and responding to more and more complex
tasks. Some of the most riveting questions in neuroscience revolve
around the ...
Clinical characterization, genetic screening and genotype-phenotype associations in cerebellar and brainstem congenital defects
(Universita degli studi di Salerno, 2020-10-01)
Cerebellar and brainstem congenital defects (CBCDs) represent a wide spectrum of malformative
disorders resulting from abnormal development of midbrain-hindbrain and characterised by high
clinical and genetic heterogeneity. ...
Cognitive and behavioral features in atypical parkinsonian syndromes
(Universita degli studi di Salerno, 2020-08-14)
Introduction Progressive supranuclear palsy (PSP), Multiple system atrophy (MSA), corticobasal degeneration (CBD) and dementia with Lewy Bodies (DLB) are included in atypical parkinsonisms (AP) and they typically involve ...
Development of a bioengineered three-dimensional scaffold able to commit stem cells toward tenogenic phenotype
(Universita degli studi di Salerno, 2021-06-23)
The term tendinopathy is a generic descriptor of tendon disorders. Spontaneous adult
tendon healing results in scar tissue formation and fibrosis, with impaired biological
and mechanical properties. Adult tendons have ...
Opportunità e rischi della longevità. Aspettative presenti e future dal punto di vista epidemiologico, ecologico, medico e sociale, soprattutto sulla base dell’esperienza dei medici
(Universita degli studi di Salerno, 2021-06-15)
Longevity is considered one of the greatest achievements of modern society. "Staying young forever" seems to be the new trend: Downgrading (i.e. being younger today than at the same age in the past) shows that there are ...