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Minimally invasive swine experimental model for the in vivo study of liver metabolism of drugs
(2012)
Purpose: To develop a clinically relevant
porcine model for the study of hepatic metabolism of drugs
by means of hepatic vein catheterization.
Materials and Methods: review of literature and
elaboration of a hypothesis, ...
Sepsis-associated encephalopathy
(2012)
Sepsis-associated encephalopathy (SAE) is defined as a diffuse or multifocal cerebral dysfunction induced by the systemic response to the infection without clinical or laboratory evidence of direct brain infection. Its ...
SiRNA delivery for control of cyclin d1 and e2f1 expression in crohn’s disease
(2017)
Evidence in inflammatory bowel diseases (IBD)
supports a connection between inflammation and cancer
due to the alteration of the cell cycle with loss of control
at the G1/S checkpoint. In this study, we analyze ...
Effect of α2-adrenergic agonists and antagonists on cytokine release from human lung macrophages cultured in vitro
(2016)
The most trusted hypothesis to explain
how α2-adrenergic agonists may preserve pulmonary
functions in critically ill patients is that they directly
act on macrophages by interfering with an
autocrine/paracrine adrenergic ...