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To be or not to be translational
(2013)
Translational Research means different things to different people, but it seems crucial to almost everyone. This discipline, although defined differently in academia, regulatory institutions, and industry, shares the ...
Accelerated bone mass senescence after hematopoietic stem cell transplantation
(2013)
Osteoporosis and avascular necrosis
(AVN) are long-lasting and debilitating complications of hematopoietic stem cell transplantation
(HSCT).
We describe the magnitude of bone loss, AVN
and impairment in osteogenic ...
Use of equine pericardium sheet (lyomesh®) as dura mater substitute in endoscopic endonasal transsphenoidal surgery
(2013)
Objective: The aim of this study was to describe the use of equine pericardium sheet (Lyomesh®) as dural substitute for sellar reconstruction after endoscopic endonasal transsphenoidal surgery for the removal of pituitary ...
Pharmacokinetics of remifentanil: a three-compartmental modeling approach
(2013)
Remifentanil is a new opioid derivative drug characterized by a fast onset and by a short time of action, since it is rapidly degraded by esterases in blood and other tissues. Its pharmacokinetic and pharmacodynamics ...
The determinants of translational medicine success - A managerial contribution
(2013)
Scope of Translational Medicine is to speed the development of new compounds of medical protocols and/or treatments to improve patient’s quality of life. Translational medicine represents the synergy between epidemiology, ...
Perioperative anaphylactic risk score for risk-oriented premedication
(2013)
Basing on the current knowledge, this paper is aimed to review the core characteristics of the most relevant therapeutic agents (steroids and antihistamines), administered to prevent perioperative anaphylaxis. Moreover, ...
Shoulder arthroplasty in osteoarthritis: current concepts in biomechanics and surgical technique
(2013)
Shoulder arthroplasty is a technically demanding procedure to restore shoulder function in patients with severe osteoarthritis of the glenohumeral joint. The modern prosthetic system exploit the benefits of modularity and ...