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Immunologic Changes in Frail Older Adults
(2014)
Several studies have shown a heightened inflammatory state in frail older adults, marked by high serum levels of interleukin-6 and C-reactive protein and an increased number of circulating leukocytes. Activation of monocytes ...
How healthy is community-dwelling elderly population? Results from southern Italy
(2015)
PURPOSE To explore the frequency of polypharmacy, functional and cognitive capacity among the elderly in Southern Italy. METHODS Populationbased retrospective cross-sectional study. Information were retrieved from ...
Models for preclinical studies in aging-related disorders: one is not for all
(2015)
Preclinical studies are essentially based on animal models of a particular disease. The primary purpose of preclinical efficacy studies is to support generalization of treatment–effect relationships to human subjects. ...
A study protocol for development and validation of a clinical prediction model for frailty (ModulEn): a new European commitment to tackling frailty
(2019)
There is a growing need to implement
and evaluate the technological solutions that allow
the early detection of age-related frailty and enable
assessment of the predictive values of frailty
components. The broad use ...
Integrated care models for managing and preventing frailty: A systematic review for the European Joint Action on Frailty Prevention (ADVANTAGE JA)
Frailty requires concerted integrated
approaches to prevent functional decline. Although
there is evidence that integrating care is effective for
older people, there is insufficient data on outcomes
from studies ...
An interregional, transdisciplinary and good practice-based approach for frailty: the mind&gait project
(2019)
Social facilities such residential
structures and day-centres increasingly seek
integrated, structured, adapted, creative, dynamic and
economic strategies to prevent frailty. The arising
need of an aged and frail ...
The european innovation partnership on active and healthy ageing synergies: protocol for a prospective observational study to measure the impact of a community-based program on prevention and mitigation of frailty (ICP –PMF) in community-dwelling older adults
(2016)
Aim of this paper is to describe the protocol of the
study “Impact of a Community-based Program on
Prevention and Mitigation of Frailty in communitydwelling older adults” developed in the framework of
the European ...
Assessing the impact of frailty on cognitive function in older adults receiving home care
(2019)
It is commonly accepted that frailty and dementia-related
cognitive decline are strongly associated. However,
degree of this association is often debated, especially in
homebound elders with disabilities. Therefore, ...