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Computational chemistry techniques for the design and the synthesis of molecules with anti-inflammatory and anti-tumor activity
(Universita degli studi di Salerno, 2019-06-18)
In the last few years, computational chemistry has played an important role in disclosing novel compounds with relevant biological activity. Inflammation and cancer processes have been recently linked, and the identification ...
Enantioselective construction of new heterocyclic scaffolds via organocatalyzed cascade reactions
(Universita degli studi di Salerno, 2019-02-04)
Chirality plays a vital role in human daily life. After the famous but tragic case regarding the Thalidomide, Food and Drug Administration (FDA) gave a guide in relation to the submission of new drug applications... [edited ...
Soft sensors in automotive applications
(Universita degli studi di Salerno, 2019-02-28)
In this work, design and validation techniques of two soft sensors for the estimation of the motorcycle vertical
dynamic have been proposed. The aim of this work is to develop soft sensors able to predict the rear and ...
Production of pharmaceutical and nutraceutical formulations for bioavailability improvement using Supercritical Assisted Atomization
(Universita degli studi di Salerno, 2019-03-13)
Industrial interest is focused on the development of new pharmaceutical and nutraceutical formulations aimed at the enhancement of bioavailability of poorly water-soluble active compounds. Various factors influence the ...
Advanced solutions for the abatement of VOCs and odours
(Universita degli studi di Salerno, 2019-03-20)
In the last decades, atmospheric pollution has become an increasingly alarming problem, due to its adverse effects at the global, regional and local scales.
In this context, the emissions of Greenhouse Gases (GHGs), ...
Ruolo del Ruxolitinib nel cross-talk tra cellule staminali mesenchimali e microambiente midollare nella mielofibrosi
(Universita degli studi di Salerno, 2019-03-13)
Introduction;
Mesenchymal stem cells (Mesenchymal Stem Cells, MSC) are one of the most studied and well-characterized adult stem cell populations. They are excellent candidates in regenerative medicine, mainly because ...
Pharmacological potential and phytochemical profile of three unexplored medicinal plants
(Universita degli studi di Salerno, 2019-02-06)
Nature is a wide source of biologically active compounds investigated with the
purpose to be used as drugs due to their biological activity and also useful in
pharmaceutical discovery and drug design. Nowadays, medicinal ...
Innovative probabilistic methodologies to assess seismic vulnerability of simple supported girder bridges
(Universita degli studi di Salerno, 2019-04-15)
Since the end of the eighties, numerous studies have been conducted analysing the relationship
between the infrastructures and the economic development of the territory, highlighting its close
correlation. In the last ...
CO2 fixation in cyclic carbonates and polycarbonates by salen-like based metal complexes
(Universita degli studi di Salerno, 2019-02-06)
At the current rate of consumption of petroleum resources, they are predicted to be exhausted within the next century. For this reason, the development of new chemical processes using biorenewable resources is attracting ...
Development of technological approaches based on supercritical fluids for the production of polymeric micro-nano particulate systems for wound healing
(Universita degli studi di Salerno, 2019-04-12)
he PhD project titled “Development of technological approaches based on supercritical fluids for the production of polymeric micro-nano particulate systems for wound healing” aimed to develop novel formulations for topical ...