Sfoglia Area Scienze mediche per Titolo
Items 1-20 di 138
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Analisi funzionale del gene UVR8 e suo ruolo nella risposta delle piante a stress ambientali
(Universita degli studi di Salerno, 2015-07-16)Plants are sessile organisms and, therefore, are continuously subjected to environmental sub-optimal or stressful conditions. In an arid environment plants are challenging multiple stresses, such, as water shortage, excessive ... -
Analysis and evaluation of potential nutracentical milk and dairy products derived from the Centrale del latte di Salerno
(Universita degli studi di Salerno, 2015-03-16)The main objective of my PhD has been focused to the analysis and characterization of milk and dairy products derived from “Centrale del Latte di Salerno” in order to assess their potential use as dietary supplements and ... -
Antioxidative and antisenescent effects of cardiac rehabilitation in heart failure patients
(Universita degli studi di Salerno, 2016-04-26)Exercise-based cardiac rehabilitation (CR) is effectively used as an adjuvant therapy in a number of cardiovascular diseases (CVDs), including chronic heart failure (CHF), and it is recommended by the American and European ... -
Application of Artificial Neural Networks to the design and optimization of superhydrophobic coatings
(2021-05-19)Recently, considerable attention has been devoted to developing superhydrophobic surfaces due to their advantageous antimicrobial and self-cleaning properties. While significant effort has been devoted to their fabrication, ... -
BAG3 extracellulare: target cellulari e molecolari
(Universita degli studi di Salerno, 2016-07-12)Bcl-2-associated athanogene 3 (BAG3) belongs to the family of co-chaperone proteins that interact with the heat shock protein 70 (Hsp70) and is involved in a number of cellular processes including proliferation and apoptosis. ... -
BAG3 role in cardiomyocytes physiopathology
(Universita degli studi di Salerno, 2013-01-31)The anti-apoptotic protein BAG3 is expressed at high levels in skeletal and cardiac muscle in vivo. Our group recently focused its interest on BAG3 role in myocardiocyte proliferation, survival and response to stressful ... -
Bioactives from agricultural food by-products: application in food and health
(Universita degli studi di Salerno, 2017-04-04)Agriculture and agri-food industry produce a large amount of residues in non-edible portions from cultivation and processing of crops. These wastes, considered by-products, give serious environment damage, if not properly ... -
Biomolecular and biophysical approaches to interrogate epigenetic targets: a platform for drug discovery
(Universita degli studi di Salerno, 2016-04-20)The term epigenetics refers to heritable changes in gene expression that do not involve changes in the DNA sequence. A large number of enzymes, which act mainly on histone tails and DNA, carries out epigenetic modifications, ... -
Biophysical investigation of biomolecules in bio-membrane models
(Universita degli studi di Salerno, 2012-05-30)Many drugs are available for the treatment of systemic or superficial mycoses, but only a limited number of them are effective antifungal drugs, devoid of toxic and undesirable side effects. Therefore there remains an ... -
Characterization and biological properties of Citrus industrial derivatives and waste products for the formulation of nutraceuticals
(Universita degli studi di Salerno, 2015-03-16)Polyphenols are natural chemical compounds, common in higher plants as and particularly known and appreciated for their health properties. We focused attention on Citrus bergamia, Citrus sinensis, Mela annurca and Vitis ... -
Chemical and biological study of natural substances active on the central nervous system
(Universita degli studi di Salerno, 2018-04-05)The research project "Chemical and biological study of natural substances active on the Central Nervous System" has been focused on the possible effects of essential oils, their main constituents (in particular monoterpenes), ... -
Chemical proteomics on ligand protein
(Universita degli studi di Salerno, 2011-03-18)The emerging field of mass spectrometry-based chemical proteomics provides a powerful instrument in the target discovery of bioactive small-molecules, such as drugs or natural products[1]. The identification of their ... -
Chimica e attività biologica di specie del genere Hypericum
(Universita degli studi di Salerno, 2013-01-14)Lo scopo di questo progetto di ricerca è stato lo studio chimico e biologico di quattro specie del genere Hypericum: H. peforatum L., H. connatum Lam, H. hircinum L., H. perfoliatum L. Nella prima fase, è stato identificato ... -
Chronotherapeutic Drug Delivery in Early Morning Pathologies: Design and Production of new NSAIDs/SAIDs polysaccharide-based systems
(Universita degli studi di Salerno, 2017-03-28)The major technological challenge encountered when formulating new dosage forms is to find a way to adapt drug release kinetics to specific clinical requirements, with the aim to enhance the therapeutic action of both new ... -
Clinical characterization, genetic screening and genotype-phenotype associations in cerebellar and brainstem congenital defects
(Universita degli studi di Salerno, 2020-10-01)Cerebellar and brainstem congenital defects (CBCDs) represent a wide spectrum of malformative disorders resulting from abnormal development of midbrain-hindbrain and characterised by high clinical and genetic heterogeneity. ... -
Cognitive and behavioral features in atypical parkinsonian syndromes
(Universita degli studi di Salerno, 2020-08-14)Introduction Progressive supranuclear palsy (PSP), Multiple system atrophy (MSA), corticobasal degeneration (CBD) and dementia with Lewy Bodies (DLB) are included in atypical parkinsonisms (AP) and they typically involve ... -
Compression and indexing of genomic data with confidentiality protection
(Universita degli studi di Salerno, 2015-04-30)The problem of data compression having specific security properties in order to guarantee user’s privacy is a living matter. On the other hand, high-throughput systems in genomics (e.g. the so-called Next Generation ... -
Computational chemistry techniques for the design and the synthesis of molecules with anti-inflammatory and anti-tumor activity
(Universita degli studi di Salerno, 2019-06-18)In the last few years, computational chemistry has played an important role in disclosing novel compounds with relevant biological activity. Inflammation and cancer processes have been recently linked, and the identification ... -
Computational design of new antimicrobial peptides
(Universita degli studi di Salerno, 2018-04-13)Antimicrobial peptides (AMP) are evolutionarily conserved components of the innate immune system. They have a broad spectrum of action against bacteria, fungi and viruses. Therefore, AMP are studied as probable substitutes ... -
Creazione di modelli virtuali 3D da immagini TC e RM per la pianificazione degli interventi chirurgici in Chirurgia Pediatrica
(Universita degli studi di Salerno, 2017-05-23)BACKGROUND. Lo sviluppo di sistemi medicali sempre più avanzati per l’acquisizione delle immagini finalizzati all’estrazione di informazioni tridimensionali sugli organi del corpo umano tramite metodi non invasivi, hanno ...