Sfoglia Scienze del farmaco per Titolo
Items 29-34 di 34
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Proteomic investigation of the impact of Cannabidiolic acid on Eukaryotic Translation complex in glioblastoma
(Universita degli studi di Salerno, 2023-04-12)Phytocannabinoids, the major secondary metabolites of cannabis plants, exert a wide range of biological activities. The present work was focused on investigating the mechanism of action of cannabidiolic acid (CBDA) in U87MG ... -
Role of CD73 in patients with advanced melanoma treated with anti-PD-1 agents
(Universita degli studi di Salerno, 2022-04-22)The treatment of metastatic melanoma was revolutionized by the approval of inhibitors of immune-checkpoints, including antibodies targeting the programmed cell death protein 1 (PD- 1), such as nivolumab and pembrolizumab. ... -
Role of H3K56 acetylation in Candida albicans virulence
(Universita degli studi di Salerno, 2022-12-20)Candida spp., especially Candida albicans, represent the third most frequent cause of infection in Intensive Care Units worldwide, with a mortality rate approaching 40%. The increasing antifungal resistance drastically ... -
Role of TFF1 in tumor progression
(Universita degli studi di Salerno, 2017-03-31)Trefoil Factor 1 (TFF1) is a small secreted protein, belonging to the trefoil factor family, characterized by a conserved “trefoil domain” containing six cysteine residues that form a three loop disulphide structure. It ... -
Targeted and untargeted proteomic approaches to disclose small molecules interactome
(Universita degli studi di Salerno, 2023-04-24)The identification of natural products and synthetic compounds target proteins is pivotal to understand their mechanism of action for the development of molecular probes and/or potential drugs. Functional proteomics is a ... -
Valorization of typical agricultural productions and related biomasses as sources of bioactive compounds
(Universita degli studi di Salerno, 2019-11-05)Main target of this PhD project was to define the metabolome of the main by-products, and in certain cases of the edible parts, of selected agroalimentary productions, that are the flowers of Opuntia ficus indica Mill. ...
