Browsing Scienze del farmaco by Title

Now showing items 30-34 of 34

    • Role of CD73 in patients with advanced melanoma treated with anti-PD-1 agents 

      Turiello, Roberta (Universita degli studi di Salerno, 2022-04-22)
      The treatment of metastatic melanoma was revolutionized by the approval of inhibitors of immune-checkpoints, including antibodies targeting the programmed cell death protein 1 (PD- 1), such as nivolumab and pembrolizumab. ...

    • Role of H3K56 acetylation in Candida albicans virulence 

      Conte, Marisa (Universita degli studi di Salerno, 2022-12-20)
      Candida spp., especially Candida albicans, represent the third most frequent cause of infection in Intensive Care Units worldwide, with a mortality rate approaching 40%. The increasing antifungal resistance drastically ...

    • Role of TFF1 in tumor progression 

      Romano, Elena (Universita degli studi di Salerno, 2017-03-31)
      Trefoil Factor 1 (TFF1) is a small secreted protein, belonging to the trefoil factor family, characterized by a conserved “trefoil domain” containing six cysteine residues that form a three loop disulphide structure. It ...

    • Targeted and untargeted proteomic approaches to disclose small molecules interactome 

      Ferraro, Giusy (Universita degli studi di Salerno, 2023-04-24)
      The identification of natural products and synthetic compounds target proteins is pivotal to understand their mechanism of action for the development of molecular probes and/or potential drugs. Functional proteomics is a ...

    • Valorization of typical agricultural productions and related biomasses as sources of bioactive compounds 

      Bottone, Alfredo (Universita degli studi di Salerno, 2019-11-05)
      Main target of this PhD project was to define the metabolome of the main by-products, and in certain cases of the edible parts, of selected agroalimentary productions, that are the flowers of Opuntia ficus indica Mill. ...