Sustainability is a global level challenge for tanning industry whose production is based on Cr(III) salts for more than 90%, negatively impacting both biotic and abiotic factors in an ecosystem. Societal challenges ...

The aim of this thesis was to explore different areas of organic chemistry in which the stereocontrol in the design of chemical processes and/or molecular assemblies is necessary. Therefore, the stereoselectivity in ...

The identification of natural products (NPs) target proteins is pivotal to understand their mechanism of action, in order to develop molecular probes and/or potential drugs. In the last 15 years, affinity chromatography-coupled ...

Negli ultimi tre decenni, l'uso dei calixareni come host macrociclici nella chimica supramolecolare ha acquisito una rilevanza crescente, soprattutto per la costruzione di macchine molecolari. Pertanto, è importante capire ...

My PhD research activity aimed to enrich the realm of peptoids1 with novel compounds and new insights into their behavior and properties, investigating their potential applications. A new class of cyclic “arylopeptoids” ...

Asymmetric organocatalysis is a new rapidly growing field whose huge potential is becoming more and more evident.This PhD project has been conceived and developed in the context of non-covalent organocatalysis. The aim of ...

In this thesis, new possible applications of electrospun scaffolds are presented. Besides, the interaction of human dermal fibroblasts (HDFs) with the materials has been investigated using multiphoton microscopy (MPM) ...

In the last year, the stable isotope ratio analysis has become a useful tool with many applications in different scientific area. In particular the characteristic isotope signature of materials has permitted to identify ...

This PhD thesis is concerned with the design, synthesis and the characterization of supramolecular scaffolds for biomimetic catalysis. Development of new organocatalytic systems based upon well-designed calix[4]arene ...

Computational methodologies in combination with experimental biological assay represent fundamental key tools in the drug discovery process. The study of ligand-macromolecule interactions has a crucial role for the design, ...