Sfoglia Translational Medicine @ UniSa per Data di Pubblicazione
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Autoimmune liver disease: news and perspectives
(2011)Autoimmune liver disorders in childhood include autoimmune hepatitis and autoimmune sclerosing cholangitis. These inflammatory liver disorders are characterised histologically by interface hepatitis, biochemically by ... -
Adrenergic mechanism in the control of endothelial function
(2011)There is considerable evidence that many disease are associated with endothelial dysfunction and reduced nitric oxide production such as hypertension, obesity, dyslipidemias, diabetes, heart failure, atherosclerosis. Notably ... -
Non-immortalized human tenocyte cultures as a vehicle for understanding cellular aspects to tendinopathy
(2011)The biochemical mechanisms underlying tendinopathy are obscure. We briefly describe preliminary observations of human tenocyte behaviour in culture as a vehicle for determining the role of reactive oxygen in tendon pathology -
Tracheostomy in spinal cord injured patients
(2011)Patients with cervical spinal cord injury frequently need prolonged mechanical ventilation as a result of worsening pulmonary vital capacity due to paralysis of respiratory muscles, severe impairment of tracheobronchial ... -
Potential clinical role of telomere length in human glioblastoma
(2011)Glioblastoma Multiforme (GBM) is the most common and lethal of human primary central nervous system (CNS) tumors. Due to the tumour’s intrinsic clinical and molecular heterogeneity, choice of initial treatment, prediction ... -
End of life in intensive care unit
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Optical tecnology developments in biomedicine: history, current and future
(2011)Biomedical optics is a rapidly emerging field for medical imaging and diagnostics. This paper reviews several biomedical optical technologies that have been developed and translated for either clinical or pre-clinical ... -
Advanced applications of robotics in digestive surgery
(2011)Laparoscopy is widely recognized as feasible and safe approach to many oncologic and benign digestive conditions and is associated with an improved early outcome. Robotic surgery promises to overcome intrinsic limitations ... -
Emergency contraception: an updated review
(2011)Emergency contraception is a common practice now. Many categories of drugs are marketed with modifications in dosage, in combination and even in the timing of administration. Recent re-analysis suggests that there is still ... -
Minimally invasive swine experimental model for the in vivo study of liver metabolism of drugs
(2012)Purpose: To develop a clinically relevant porcine model for the study of hepatic metabolism of drugs by means of hepatic vein catheterization. Materials and Methods: review of literature and elaboration of a hypothesis, ... -
Sisters acts: converging signaling between CaMKII and CaMKIV, two members of the same family
(2012)Calcium (Ca2+ ) is a universal second messenger that regulates a number of diverse cellular processes including cell proliferation, development, motility, secretion, learning and memory1, 2. A variety of stimuli, such ... -
Pediatric health mobility: is it only an italian problem?
(2012)Intra-regional, extra-regional and international health mobility are important phenomena for regional and national healthcare planning. Pediatric data on this topic are scarce. We therefore conducted a systematic ... -
Estrogens and neuropeptides in postmenopausal women: un update
(2012)Menopause is characterized by depletion of ovarian follicles, a reduction of ovarian hormones to castrate levels and elevated levels of serum gonadotropins from the anterior pituitary gland. Although this process has ... -
Prognostic differences between VAP caused by Acinetobacter baumannii and VAP caused by other microorganisms
(2012)Nosocomial infection, in particular pneumonia, is an important risk factor for hospital mortality and morbidity. Acinetobacter baumannii is a common multi-resistant microorganism responsible of Ventilator Associated Pneumonia ... -
Economic evaluation of “pulse dose” radiofrequency in the treatment of occipital neuralgia headache
(2012)Headache occipital neuralgia is an example of pain-disease for which treatment both pharmacological protocols and invasive methods are used. Among the latter, the RF (Radiofrequency) pulse-dose has been of interest for the ... -
A polymorphism within the promoter of the dopamine receptor D1 (DRD1 -48A7G) associates with impaired kidney function in white hypertensive patients
(2012)Dopamine DRD1 receptor regulates renal function and vascular resistance. It plays a role in the pathogenesis of hypertension in animal models. In humans, the DRD1 gene presents a A-48G polymorphism associated to hypertension ... -
Allergens in allergy diagnosis: a glimpse at emerging new concepts and methodologies
(2012)Allergic diseases are important concern of public health. A reliable diagnosis is of utmost importance for the management of allergic patients both when immunotherapy is planned and when the treatment is essentially based ... -
Environmental pollution effectson reproductive health? Clinical-epidemiological study in southern Italy
(2012)This study aims to address the clinical, statistical and Epidemiological Relationship Between Birth Defects and Environmental Pollution, in the Campania Region and in Salerno. Objectives: We examined four groups of subjects ...